If you are have issues with Skype: Upgrade to 0.9.2805-1 (or newer).

(Skype is now fully supported by MobileSubstrate: you can now activate any extensions you want. While specific extensions may be buggy it is not something that I can fix in MobileSubstrate. ;P)

Mobile Safe Mode is a feature designed to protect you when extensions like IntelliScreen crash.

Support framework used by iPhone projects such as WinterBoard, Dock2, and Five Icon Dock.

The general idea is that there are a number of reasons one might want to hook functionality into an existing application. In order to do this there are a few dangerous or complex steps. By centralizing the code for these we can hope to get them right.

As an example, MobileSubstrate provides a simple platform (one integrated with Cydia) for deploying code that gets inserted into graphical applications. Eventually it will be able to provide error handling and fallback support (think of a "Safe Mode").

As a library, it has started taking on generalized versions of the code in WinterBoard to be able to rapidly generate application hooks. Is not yet documented, but will be when I get the time (hopefully soon?).